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QuikClot, TraumaDEX og Hemcom

here is a intro paper from swatdoctor.com: Blood Clotters Article from Police Magazine August 2004

 

http://www.chinookmed.com/detail.php...limit_start=10

It’s a hot topic right now so I thought I would do a side-by-side comparison of the QuikClot and TraumaDEX products. Both are extremely effective and over lap a great deal in their features and benefits yet have enough of a difference to make sure you have the right product for your application. Check it out.

TraumaDEX

Material: Plant based polysaccharide source

Technology: Microporous Polysaccharide Hemosphere (MPH) – accelerate natural hemostasis by concentrating blood solids to form a gel around the particles

Dose/Packaging: 0.5, 2 or 5 gram (powder) applicators in sterile, waterproof packages with instructions

Price (Chinook): $23.95 (5 gram)

Best for: Topical dressing for temporary treatment of severely bleeding wounds such as surgical wounds (post-operative, donor sites, dermatological), cuts, lacerations, and traumatic injuries. For professional use only.

Pros:

• Easy application, can be self administered
• No irrigation needed, reabsorbed naturally
• Hypoallergenic
• Bio-inert - No risk of disease transmission
• Safe while in transit to a medical facility
• Extended shelf life (3-5 yrs)
• No exothermic reaction

Cons:

• Not intended for patients allergic to starch products
• In case studies, TraumaDEX does not perform as well in cases of severe arterial and venous bleeding.

QuikClot

Material: Derivative of volcanic rock

Technology: Absorbent Hemostatic Agent – instead of adding clotting factors, QuikClot granules extract (absorb) fluids concentrating clotting factors creating a matrix for clot formation

Dose/Packaging: 2-1.75 or 1-3.5 oz (granular) sterile, vacuum packed, waterproof packages with instructions

Price (Chinook): $23.95 (3.5 oz)

Best for: External temporary traumatic wound treatment to stop moderate-to-severe bleeding in large wounds, including high-volume venous and arterial bleeding. Typically used upon determination that conventional methods have been inadequate to stop bleeding.

Pros:

• Easy application, can be self administered
• Easy removal with irrigation or aspiration
• Non-allergenic
• Chemically inert - No risk of disease transmission
• Safe to leave in the wound while in transit to a medical facility
• Extended shelf life (3 yrs)

Cons:

• Exothermic reaction – thermal increase is directly proportional to the ratio of QuikClot and blood. Thermal reaction is minimized by removing excess moisture on or near the wound and only using as much as you need (no more than 2:1 ratio QuikClot to blood).

For at home treatment by individuals of minor cuts, scrapes, abrasions, punctures and other minor wounds, there is BLEED-X from the makers of TraumaDEX using the same MPH technology packaged in 0.5 gram dispenser with a 2”x2” gauze pad. It is also recommended for use by individuals on blood thinners.

All information was researched from the following resources: www.medafor.com, www.z-medica.com, printed literature from the manufacturers.

Procedures for first responders' application of Quikclot hemostatic agent

Journal Articles quickclot( fra www.z-medica.com )

7/1/2005 - Hemostatic efficacy of two advanced dressings in an aortic hemorrhage model in Swine.    

1/17/2005 - Hemorrhage control in the battlefield: role of new hemostatic agents.    

5/1/2004 - Application Of A Zeolite Hemostatic Agent Achieves 100% Survival In A Lethal Model Of Complex Groin Injury    

1/1/2004 - Intracorporeal Use Of The Hemostatic Agent QuickClot In A Coagulopathic Patient With Combined Thoracoabdominal Penetrating Trauma.    

6/1/2003 - Comparative Analysis Of Hemostatic Agents In A Swine Model Of Lethal Groin Injury

Hemcom

ud over QC og traumadex er der også Hemcom på market.

fra: http://www.popsci.com

Half of all deaths on the battlefield are due to uncontrollable bleeding. And though gauze is often no match for spurting wounds, the bloodthirsty HemCon Bandage is: It contains positively charged chitosan molecules, extracted from shrimp shells, that attract negatively charged red blood cells. As the cells are pulled into the bandage, they create a tight-fitting plug over the wound. "You can have a hole in your heart and 60 seconds later it's sealed," says HemCon inventor Kenton Gregory. The bandage made its debut in the 2003 Iraq war and was FDA-approved for nonprescription use in August. At $100 for a 4-by-4-inch square, it may sound expensive, but if the situation calls for it, we're guessing it'll seem like a serious bargain.

http://www.hemcon.com/

The HemCon® Bandage is an FDA cleared pliable, sterile, chitosan dressing capable of stopping severe external hemorrhage following trauma and penetrating injury.
The HemCon® Bandage significantly outperformed the standard of care (gauze) with significant improvements in survival, blood loss, and the number of applications of either pressure or dressings required to achieve hemostasis.

* Manufactured from a natural product called chitosan, fabricated into a flat bandage using proprietary techniques
* Supplied sterile in a sealed foil vapor barrier package
* Labeled for single use only
* Stable at room temperature.

* Can be supplied in various sizes.
* Currently only available in 4" x 4"
* Provides rapid control of moderate and severe external hemorrhage
* Simple to use
* Cost effective
* Adheres tightly to the site of the application
* Forms a strong durable non-occlusive clot
* Seals the injury site to further bleeding and external infective agents
* Forms an antibacterial barrier, reducing the potential for infection.

 

HemCon featured on CNN (video)


The HemCon® Bandage is safe, durable, highly effective, and does not contain human proteins or clotting factors.

pris (Chinook): 165$ ved 1 stk.

skema fra min powerpoint om hæmostatiske forbindinger

 

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Marine Polymer Dressing (RDH)

 

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kilde: SOMA powerpoint af  Alan Murdock Maj, MC USAFVice-Chief Trauma Care ServicesWilford Hall Air Force Medical CenterLackland AFB, TX, Trauma Resuscitation and Tactics:Refinement and Field Use

 

Development of Hemostatic Dressings for Use in Military

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 Copyright Frank Hansen 2006
Last updated: 07/09/07.